Iron oxide pigments and mica create most color variations in mineral makeup. Most iron oxide pigments used in cosmetics are approved by the FDA. When used in extremely high concentrations—for example, during tattooing and permanent pigmentation of eyebrows and lashes—iron oxides can cause irritation, but in mineral makeup the concentration is far lower. If you have a family history of allergies, you will be better off with plant-based kohl eyeliners instead of dark mineral eye shadows. Read more of this post